OREXIGEN THERAPEUTICS INC (OREX)

Overview Price 3.33 Price Change Today -$0.10 (-2.92%) P&P rating Zacks Rank 3 - HOLD Open Price $3.41 Previous Close $3.43 Daily Range $3.30 - $3.44 52-Week Range $1.22 - $5.14 Volume 477,358 OREXIGEN THERAPEUTICS, INC. is a biopharmaceutical company focused on the development of pharmaceutical product candidates for the treatment of central nervous system disorders, including obesity. The Company's lead combination product candidates targeted for obesity are Contrave, which is in Phase III clinical trials, and Empatic, which is in the later stages of Phase II clinical development. Both product candidates are designed to take advantage of the Company's understanding of how the brain appears to regulate appetite and energy expenditure, as well as the mechanisms that come into play to limit weight loss over time. Each product candidate is designed to act on a specific group of neurons in the central nervous system with the goal of achieving appetite suppression and sustained weight loss. Other Resources for OREX Detailed Quote Earnings Estimates Company Report Interactive Chart Commentary Zacks Blog: Zacks' Voice of the People highlights opportunities with Starbucks, Realty Income, Keryx Biopharma, Bon-Ton Stores and Orexigen Therapeutics April 12, 2012 Zacks Blog: Latest RTMB Trades April 11, 2012 Zacks Blog: Arena Pharma Drug under EU Review March 27, 2012 Zacks Blog: Arena Pharma Files Response to CRL January 6, 2012 Zacks Blog: Zacks #1 Rank Additions for Thursday December 8, 2011 OREXIGEN THERAPEUTICS, INC. is a biopharmaceutical company focused on the development of pharmaceutical product candidates for the treatment of central nervous system disorders, including obesity. The Company's lead combination product candidates targeted for obesity are Contrave, which is in Phase III clinical trials, and Empatic, which is in the later stages of Phase II clinical development. Both product candidates are designed to take advantage of the Company's understanding of how the brain appears to regulate appetite and energy expenditure, as well as the mechanisms that come into play to limit weight loss over time. Each product candidate is designed to act on a specific group of neurons in the central nervous system with the goal of achieving appetite suppression and sustained weight loss.   Brokerage Analyst Recommendations 6 Brokerage Firms Covering OREX   Strong Buy 2 Buy 0 Hold 4 Sell 0 Strong Sell 0 Average Broker Recommendation (ABR): 2.33   OREX Ratings: BUY  SELL  HOLD OREX Consensus Forecasts

Rate this Stock! You haven't rated this stock yet! Ticker Call Buy Sell Analysis Time Frame Week or Less Week to a Month One to Three Months Three to Six Months Six Months to a Year One to Three Years Three Plus Years What The Community Thinks Total Players 5 Buy 1 Sell   Top Buy Analysis BUY: OREX Company: OREXIGEN THERAPEUTICS INC Points: -65.33 Start Price: $6.84 Start Date: 05/11/2010 8:45 PM jdfthree P&P Score: 98.44 Recs: New Diet drug in pipeline which should explode shortly! Comments: 0 | Comment More Recent Analysis Top Sell Analysis SELL: OREX Company: OREXIGEN THERAPEUTICS INC Points: 90.69 Start Price: $9.59 Start Date: 09/24/2009 11:09 PM BetterThanYou P&P Score: 98.30 Recs: Comments: 0 | Comment More Recent Analysis

Blog Posts

User	User Score	Date	Title	Comments	Last Comment
zantriocom	0.00	07/20/09	Zantrio.com Stock Picks for July 20, 2009	0
Zacks_Analysts	0.00	03/27/12	Arena Pharma Drug under EU Review - Analyst Blog	0
Zacks_Analysts	0.00	01/06/12	Arena Pharma Files Response to CRL - Analyst Blog	0
Zacks_Analysts	0.00	09/22/11	Lifeline for Orexigen's Contrave - Analyst Blog	0
Zacks_Analysts	0.00	06/06/11	Another Blow for Orexigen's Contrave - Analyst Blog	0
Zacks_Analysts	0.00	05/05/11	Vivus Loss Narrower than Expected - Analyst Blog	0
Zacks_Analysts	0.00	03/18/11	Loss at OREX Narrower than Expected - Analyst Blog	0
Zacks_Analysts	0.00	03/17/11	Revenues Rise at ARNA - Analyst Blog	0
Zacks_Analysts	0.00	02/02/11	Setback for Orexigen - Analyst Blog	0
Zacks_Analysts	0.00	12/27/10	Vivus Seeks EU Nod for Qnexa - Analyst Blog	0

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Commentary

BUY: OREXIGEN THERAPEUTICS INC (OREX) Start Price: $5.91 Points: -59.28 Created: 09/21/2010 beginning of a nice rally Comments: 0 | Comment BIGZEE Recs:

BUY: OREXIGEN THERAPEUTICS INC (OREX) Start Price: $5.48 Points: -56.85 Created: 08/03/2010 Orexigen Therapeutics, Inc., a biopharmaceutical company, focuses on the development of pharmaceutical product candidates for the treatment of obesity. Its lead combination product candidates include Contrave, which has completed Phase III clinical trials; and Empatic that has completed Phase II clinical trials. Contrave is a combination of two drugs, bupropion and naltrexone, in a sustained release formulation (SR). Bupropion is an antidepressant and smoking cessation medication; naltrexone is a treatment for alcohol and opioid addiction. The company's Empatic product candidate is a combination of bupropion SR and zonisamide SR. Zonisamide, in an immediate release formulation for the adjunctive treatment of partial seizures, a form of epilepsy. The company was founded in 2002 and is based in La Jolla, California. Comments: 0 | Comment hangash Recs:

BUY: OREXIGEN THERAPEUTICS INC (OREX) Start Price: $6.84 Points: -65.33 Created: 05/11/2010 New Diet drug in pipeline which should explode shortly! Comments: 0 | Comment jdfthree Recs:

BUY: OREXIGEN THERAPEUTICS INC (OREX) Start Price: $8.96 Points: -89.05 Created: 09/10/2009 Great moves on solid volume. Looks like it wants to keep running. Comments: 0 | Comment OnIslandTrader Recs:

BUY: OREXIGEN THERAPEUTICS INC (OREX) Start Price: $4.75 Points: -49.03 Created: 07/28/2010 Comments: 0 | Comment HardTimes Recs:

SELL: OREXIGEN THERAPEUTICS INC (OREX) Start Price: $9.59 Points: +90.69 Created: 09/24/2009 Comments: 0 | Comment BetterThanYou Recs:

Picks

Username	P&P Score	Call	Time Frame	Start Date	Start Price	Today (change)	Stock Gain	S&P Gain	Points	Analysis
BIGZEE	3.54	BUY	Week or Less	09/21/2010	$5.91	$3.33 (0.00%)	-43.65%	+15.62%	-59.28	view close
hangash	0.57	BUY	Six Months to a Year	08/03/2010	$5.48	$3.33 (0.00%)	-39.23%	+17.61%	-56.85	view close
HardTimes	0.36	BUY	One to Three Months	07/28/2010	$4.75	$3.33 (0.00%)	-29.89%	+19.14%	-49.03
jdfthree	98.44	BUY	Week or Less	05/11/2010	$6.84	$3.33 (0.00%)	-51.32%	+14.02%	-65.33	view close
BetterThanYou	98.30	SELL	Week to a Month	09/24/2009	$9.59	$3.33 (0.00%)	-65.28%	+25.41%	+90.69
OnIslandTrader	0.43	BUY	One to Three Months	09/10/2009	$8.96	$3.33 (0.00%)	-62.83%	+26.21%	-89.05	view close